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CD73 promotes proliferation and migration of human cervical cancer cells independent of its enzyme activity

BACKGROUND: CD73 has both enzymatic and non-enzymatic functions in cells. As a nucleotidase, CD73 plays its enzymatic function by catalyzing the hydrolysis of AMP into adenosine and phosphate. In addition to this, accumulating data have shown that CD73 is a key regulatory molecule involved in cancer...

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Detalles Bibliográficos
Autores principales: Gao, Zhao-wei, Wang, Hui-ping, Lin, Fang, Wang, Xi, Long, Min, Zhang, Hui-zhong, Dong, Ke
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5311855/
https://www.ncbi.nlm.nih.gov/pubmed/28202050
http://dx.doi.org/10.1186/s12885-017-3128-5