The influence of AccD5 on AccD6 carboxyltransferase essentiality in pathogenic and non-pathogenic Mycobacterium

Malonyl-coenzyme A (CoA) is a crucial extender unit for the synthesis of mycolic and other fatty acids in mycobacteria, generated in a reaction catalyzed by acetyl-CoA carboxylase. We previously reported on the essentiality of accD6(Mtb) encoding the functional acetyl-CoA carboxylase subunit in Myco...

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Detalles Bibliográficos
Autores principales: Pawelczyk, Jakub, Viljoen, Albertus, Kremer, Laurent, Dziadek, Jaroslaw
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5311964/
https://www.ncbi.nlm.nih.gov/pubmed/28205597
http://dx.doi.org/10.1038/srep42692

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5311964/
https://www.ncbi.nlm.nih.gov/pubmed/28205597
http://dx.doi.org/10.1038/srep42692

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