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The influence of AccD5 on AccD6 carboxyltransferase essentiality in pathogenic and non-pathogenic Mycobacterium
Malonyl-coenzyme A (CoA) is a crucial extender unit for the synthesis of mycolic and other fatty acids in mycobacteria, generated in a reaction catalyzed by acetyl-CoA carboxylase. We previously reported on the essentiality of accD6(Mtb) encoding the functional acetyl-CoA carboxylase subunit in Myco...
Autores principales: | Pawelczyk, Jakub, Viljoen, Albertus, Kremer, Laurent, Dziadek, Jaroslaw |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5311964/ https://www.ncbi.nlm.nih.gov/pubmed/28205597 http://dx.doi.org/10.1038/srep42692 |
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