Hypoxia-induced angiotensin II by the lactate-chymase-dependent mechanism mediates radioresistance of hypoxic tumor cells

The renin-angiotensin system (RAS) is a principal determinant of arterial blood pressure and fluid and electrolyte balance. RAS component dysregulation was recently found in some malignancies and correlated with poor patient outcomes. However, the exact mechanism of local RAS activation in tumors is...

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Detalles Bibliográficos
Autores principales: Xie, Guozhu, Liu, Ying, Yao, Qiwei, Zheng, Rong, Zhang, Lanfang, Lin, Jie, Guo, Zhaoze, Du, Shasha, Ren, Chen, Yuan, Quan, Yuan, Yawei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5311966/
https://www.ncbi.nlm.nih.gov/pubmed/28205588
http://dx.doi.org/10.1038/srep42396

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5311966/
https://www.ncbi.nlm.nih.gov/pubmed/28205588
http://dx.doi.org/10.1038/srep42396

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