Immature mice are more susceptible than adult mice to acetaminophen-induced acute liver injury

Acetaminophen (APAP) overdose induces acute liver injury. The aim of the present study was to analyze the difference of susceptibility between immature and adult mice to APAP-induced acute liver injury. Weanling immature and adult mice were injected with APAP (300 mg/kg). As expected, immature mice...

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Detalles Bibliográficos
Autores principales: Lu, Yan, Zhang, Cheng, Chen, Yuan-Hua, Wang, Hua, Zhang, Zhi-Hui, Chen, Xi, Xu, De-Xiang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5311972/
https://www.ncbi.nlm.nih.gov/pubmed/28205631
http://dx.doi.org/10.1038/srep42736

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5311972/
https://www.ncbi.nlm.nih.gov/pubmed/28205631
http://dx.doi.org/10.1038/srep42736

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