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Immature mice are more susceptible than adult mice to acetaminophen-induced acute liver injury
Acetaminophen (APAP) overdose induces acute liver injury. The aim of the present study was to analyze the difference of susceptibility between immature and adult mice to APAP-induced acute liver injury. Weanling immature and adult mice were injected with APAP (300 mg/kg). As expected, immature mice...
Autores principales: | Lu, Yan, Zhang, Cheng, Chen, Yuan-Hua, Wang, Hua, Zhang, Zhi-Hui, Chen, Xi, Xu, De-Xiang |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5311972/ https://www.ncbi.nlm.nih.gov/pubmed/28205631 http://dx.doi.org/10.1038/srep42736 |
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