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FocusHeuristics – expression-data-driven network optimization and disease gene prediction

To identify genes contributing to disease phenotypes remains a challenge for bioinformatics. Static knowledge on biological networks is often combined with the dynamics observed in gene expression levels over disease development, to find markers for diagnostics and therapy, and also putative disease...

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Detalles Bibliográficos
Autores principales: Ernst, Mathias, Du, Yang, Warsow, Gregor, Hamed, Mohamed, Endlich, Nicole, Endlich, Karlhans, Murua Escobar, Hugo, Sklarz, Lisa-Madeleine, Sender, Sina, Junghanß, Christian, Möller, Steffen, Fuellen, Georg, Struckmann, Stephan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5311990/
https://www.ncbi.nlm.nih.gov/pubmed/28205611
http://dx.doi.org/10.1038/srep42638