Cargando…
FocusHeuristics – expression-data-driven network optimization and disease gene prediction
To identify genes contributing to disease phenotypes remains a challenge for bioinformatics. Static knowledge on biological networks is often combined with the dynamics observed in gene expression levels over disease development, to find markers for diagnostics and therapy, and also putative disease...
Autores principales: | Ernst, Mathias, Du, Yang, Warsow, Gregor, Hamed, Mohamed, Endlich, Nicole, Endlich, Karlhans, Murua Escobar, Hugo, Sklarz, Lisa-Madeleine, Sender, Sina, Junghanß, Christian, Möller, Steffen, Fuellen, Georg, Struckmann, Stephan |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2017
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5311990/ https://www.ncbi.nlm.nih.gov/pubmed/28205611 http://dx.doi.org/10.1038/srep42638 |
Ejemplares similares
-
Combination of the PI3K inhibitor Idelalisib with the conventional cytostatics cytarabine and dexamethasone leads to changes in pathway activation that induce anti-proliferative effects in B lymphoblastic leukaemia cell lines
por: Sklarz, L.-M., et al.
Publicado: (2020) -
ExprEssence - Revealing the essence of differential experimental data in the context of an interaction/regulation net-work
por: Warsow, Gregor, et al.
Publicado: (2010) -
Molecular Characterization of the Response to Conventional Chemotherapeutics in Pro-B-ALL Cell Lines in Terms of Tumor Relapse
por: Gladbach, Yvonne Saara, et al.
Publicado: (2022) -
Novel Microscopic Techniques for Podocyte Research
por: Siegerist, Florian, et al.
Publicado: (2018) -
Differential Network Analysis Applied to Preoperative Breast Cancer Chemotherapy Response
por: Warsow, Gregor, et al.
Publicado: (2013)