Protective Effect of 17β-Estradiol Upon Hippocampal Spine Density and Cognitive Function in an Animal Model of Vascular Dementia

The current study examined whether the steroid hormone, 17β-estradiol (E2) can exert long-lasting beneficial effects upon axonal health, synaptic plasticity, dementia-related amyloid-beta (Aβ) protein expression, and hippocampal-dependent cognitive function in an animal model of chronic cerebral hyp...

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Detalles Bibliográficos
Autores principales: Zhu, Ying, Zhang, Quanguang, Zhang, Wenli, Li, Ning, Dai, Yongxin, Tu, Jingyi, Yang, Fang, Brann, Darrell W., Wang, Ruimin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5311994/
https://www.ncbi.nlm.nih.gov/pubmed/28205591
http://dx.doi.org/10.1038/srep42660

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5311994/
https://www.ncbi.nlm.nih.gov/pubmed/28205591
http://dx.doi.org/10.1038/srep42660

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