CXCR2 deficient mice display macrophage-dependent exaggerated acute inflammatory responses

CXCR2 is an essential regulator of neutrophil recruitment to inflamed and damaged sites and plays prominent roles in inflammatory pathologies and cancer. It has therefore been highlighted as an important therapeutic target. However the success of the therapeutic targeting of CXCR2 is threatened by o...

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Detalles Bibliográficos
Autores principales: Dyer, Douglas P., Pallas, Kenneth, Ruiz, Laura Medina, Schuette, Fabian, Wilson, Gillian J., Graham, Gerard J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5311995/
https://www.ncbi.nlm.nih.gov/pubmed/28205614
http://dx.doi.org/10.1038/srep42681

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5311995/
https://www.ncbi.nlm.nih.gov/pubmed/28205614
http://dx.doi.org/10.1038/srep42681

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