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Mosaic expression of Atrx in the mouse central nervous system causes memory deficits

The rapid modulation of chromatin organization is thought to play a crucial role in cognitive processes such as memory consolidation. This is supported in part by the dysregulation of many chromatin-remodelling proteins in neurodevelopmental and psychiatric disorders. A key example is ATRX, an X-lin...

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Detalles Bibliográficos
Autores principales: Tamming, Renee J., Siu, Jennifer R., Jiang, Yan, Prado, Marco A. M., Beier, Frank, Bérubé, Nathalie G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Company of Biologists Ltd 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5312007/
https://www.ncbi.nlm.nih.gov/pubmed/28093507
http://dx.doi.org/10.1242/dmm.027482