Jmjd2c facilitates the assembly of essential enhancer-protein complexes at the onset of embryonic stem cell differentiation

Jmjd2 H3K9 demethylases cooperate in promoting mouse embryonic stem cell (ESC) identity. However, little is known about their importance at the exit of ESC pluripotency. Here, we reveal that Jmjd2c facilitates this process by stabilising the assembly of mediator-cohesin complexes at lineage-specific...

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Detalles Bibliográficos
Autores principales: Tomaz, Rute A., Harman, Jennifer L., Karimlou, Donja, Weavers, Lauren, Fritsch, Lauriane, Bou-Kheir, Tony, Bell, Emma, del Valle Torres, Ignacio, Niakan, Kathy K., Fisher, Cynthia, Joshi, Onkar, Stunnenberg, Hendrik G., Curry, Edward, Ait-Si-Ali, Slimane, Jørgensen, Helle F., Azuara, Véronique
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Company of Biologists Ltd 2017
Materias:
Stem Cells and Regeneration
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5312034/
https://www.ncbi.nlm.nih.gov/pubmed/28087629
http://dx.doi.org/10.1242/dev.142489

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5312034/
https://www.ncbi.nlm.nih.gov/pubmed/28087629
http://dx.doi.org/10.1242/dev.142489

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