Genetic Predisposition To Acquire a Polybasic Cleavage Site for Highly Pathogenic Avian Influenza Virus Hemagglutinin

Highly pathogenic avian influenza viruses with H5 and H7 hemagglutinin (HA) subtypes evolve from low-pathogenic precursors through the acquisition of multiple basic amino acid residues at the HA cleavage site. Although this mechanism has been observed to occur naturally only in these HA subtypes, li...

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Detalles Bibliográficos
Autores principales: Nao, Naganori, Yamagishi, Junya, Miyamoto, Hiroko, Igarashi, Manabu, Manzoor, Rashid, Ohnuma, Aiko, Tsuda, Yoshimi, Furuyama, Wakako, Shigeno, Asako, Kajihara, Masahiro, Kishida, Noriko, Yoshida, Reiko, Takada, Ayato
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2017
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5312086/
https://www.ncbi.nlm.nih.gov/pubmed/28196963
http://dx.doi.org/10.1128/mBio.02298-16

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5312086/
https://www.ncbi.nlm.nih.gov/pubmed/28196963
http://dx.doi.org/10.1128/mBio.02298-16

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