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Meningeal retinoic acid contributes to neocortical lamination and radial migration during mouse brain development
Retinoic acid (RA) is a diffusible molecule involved in early forebrain patterning. Its later production in the meninges by the retinaldehyde dehydrogenase RALDH2 coincides with the time of cortical neuron generation. A function of RA in this process has not been adressed directly as Raldh2(−/−) mou...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Company of Biologists Ltd
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5312094/ https://www.ncbi.nlm.nih.gov/pubmed/28011626 http://dx.doi.org/10.1242/bio.021063 |