Frequency, severity and related factors of androgenetic alopecia in dermatology outpatient clinic: hospital-based cross-sectional study in Turkey

BACKGROUND: Androgenetic alopecia (AGA) is a patterned hair loss occurring due to systemic androgen and genetic factors. It is the most common cause of hair loss in both genders. In recent years, many studies investigating the relation between systemic diseases and androgenetic alopecia presented co...

Descripción completa

Detalles Bibliográficos
Autores principales: Salman, Kubra Esen, Altunay, Ilknur Kivanc, Kucukunal, Nihal Asli, Cerman, Asli Aksu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Sociedade Brasileira de Dermatologia 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5312176/
https://www.ncbi.nlm.nih.gov/pubmed/28225954
http://dx.doi.org/10.1590/abd1806-4841.20175241
_version_ 1782508154352828416
author Salman, Kubra Esen
Altunay, Ilknur Kivanc
Kucukunal, Nihal Asli
Cerman, Asli Aksu
author_facet Salman, Kubra Esen
Altunay, Ilknur Kivanc
Kucukunal, Nihal Asli
Cerman, Asli Aksu
author_sort Salman, Kubra Esen
collection PubMed
description BACKGROUND: Androgenetic alopecia (AGA) is a patterned hair loss occurring due to systemic androgen and genetic factors. It is the most common cause of hair loss in both genders. In recent years, many studies investigating the relation between systemic diseases and androgenetic alopecia presented controversial results. OBJECTIVES: In this study we aimed to investigate the frequency of androgenetic alopecia, the presence of accompanying systemic diseases, the relation between body mass index and androgenetic alopecia severity and the association of hyperandrogenemia signs with androgenetic alopecia in patients who referred to our outpatient clinic. METHODS: Patients who referred to our clinic between October 2013 and May 2014 were included in the study. Diagnosis of androgenetic alopecia was made upon clinical findings. Presence of seborrhea and acne in both genders, and hirsutism in women, were examined. Age, gender, smoking habit and alcohol consumption, age of onset of androgenetic alopecia, family history, accompanying systemic diseases and abnormalities of menstrual cycle were recorded. RESULTS: 954 patients (535 women, 419 men) were included in the study. Androgenetic alopecia prevalence found was 67.1% in men and 23.9% in women. Androgenetic alopecia prevalence and severity were correlated with age in both genders (p=0,0001). Frequency of accompanying systemic diseases were not significantly different between patients with and without androgenetic alopecia (p=0,087), except for hypertension, which was significantly more frequent in men with androgenetic alopecia aged between 50 and 59 years. Study limitations: Despite the exclusion of other causes of alopecia, differentiation of Ludwig grade 1 AGA from telogen effluvium based on clinical features alone is difficult. CONCLUSIONS: In our study the rate of androgenetic alopecia was found to be higher than the other studies made in Asian and Caucasian populations.
format Online
Article
Text
id pubmed-5312176
institution National Center for Biotechnology Information
language English
publishDate 2017
publisher Sociedade Brasileira de Dermatologia
record_format MEDLINE/PubMed
spelling pubmed-53121762017-02-23 Frequency, severity and related factors of androgenetic alopecia in dermatology outpatient clinic: hospital-based cross-sectional study in Turkey Salman, Kubra Esen Altunay, Ilknur Kivanc Kucukunal, Nihal Asli Cerman, Asli Aksu An Bras Dermatol Investigation BACKGROUND: Androgenetic alopecia (AGA) is a patterned hair loss occurring due to systemic androgen and genetic factors. It is the most common cause of hair loss in both genders. In recent years, many studies investigating the relation between systemic diseases and androgenetic alopecia presented controversial results. OBJECTIVES: In this study we aimed to investigate the frequency of androgenetic alopecia, the presence of accompanying systemic diseases, the relation between body mass index and androgenetic alopecia severity and the association of hyperandrogenemia signs with androgenetic alopecia in patients who referred to our outpatient clinic. METHODS: Patients who referred to our clinic between October 2013 and May 2014 were included in the study. Diagnosis of androgenetic alopecia was made upon clinical findings. Presence of seborrhea and acne in both genders, and hirsutism in women, were examined. Age, gender, smoking habit and alcohol consumption, age of onset of androgenetic alopecia, family history, accompanying systemic diseases and abnormalities of menstrual cycle were recorded. RESULTS: 954 patients (535 women, 419 men) were included in the study. Androgenetic alopecia prevalence found was 67.1% in men and 23.9% in women. Androgenetic alopecia prevalence and severity were correlated with age in both genders (p=0,0001). Frequency of accompanying systemic diseases were not significantly different between patients with and without androgenetic alopecia (p=0,087), except for hypertension, which was significantly more frequent in men with androgenetic alopecia aged between 50 and 59 years. Study limitations: Despite the exclusion of other causes of alopecia, differentiation of Ludwig grade 1 AGA from telogen effluvium based on clinical features alone is difficult. CONCLUSIONS: In our study the rate of androgenetic alopecia was found to be higher than the other studies made in Asian and Caucasian populations. Sociedade Brasileira de Dermatologia 2017 /pmc/articles/PMC5312176/ /pubmed/28225954 http://dx.doi.org/10.1590/abd1806-4841.20175241 Text en ©2017 by Anais Brasileiros de Dermatologia http://creativecommons.org/licenses/by-nc/4.0/ This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License which permits unrestricted non-commercial use, distribution, and reproduction in any medium provided the original work is properly cited.
spellingShingle Investigation
Salman, Kubra Esen
Altunay, Ilknur Kivanc
Kucukunal, Nihal Asli
Cerman, Asli Aksu
Frequency, severity and related factors of androgenetic alopecia in dermatology outpatient clinic: hospital-based cross-sectional study in Turkey
title Frequency, severity and related factors of androgenetic alopecia in dermatology outpatient clinic: hospital-based cross-sectional study in Turkey
title_full Frequency, severity and related factors of androgenetic alopecia in dermatology outpatient clinic: hospital-based cross-sectional study in Turkey
title_fullStr Frequency, severity and related factors of androgenetic alopecia in dermatology outpatient clinic: hospital-based cross-sectional study in Turkey
title_full_unstemmed Frequency, severity and related factors of androgenetic alopecia in dermatology outpatient clinic: hospital-based cross-sectional study in Turkey
title_short Frequency, severity and related factors of androgenetic alopecia in dermatology outpatient clinic: hospital-based cross-sectional study in Turkey
title_sort frequency, severity and related factors of androgenetic alopecia in dermatology outpatient clinic: hospital-based cross-sectional study in turkey
topic Investigation
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5312176/
https://www.ncbi.nlm.nih.gov/pubmed/28225954
http://dx.doi.org/10.1590/abd1806-4841.20175241
work_keys_str_mv AT salmankubraesen frequencyseverityandrelatedfactorsofandrogeneticalopeciaindermatologyoutpatientclinichospitalbasedcrosssectionalstudyinturkey
AT altunayilknurkivanc frequencyseverityandrelatedfactorsofandrogeneticalopeciaindermatologyoutpatientclinichospitalbasedcrosssectionalstudyinturkey
AT kucukunalnihalasli frequencyseverityandrelatedfactorsofandrogeneticalopeciaindermatologyoutpatientclinichospitalbasedcrosssectionalstudyinturkey
AT cermanasliaksu frequencyseverityandrelatedfactorsofandrogeneticalopeciaindermatologyoutpatientclinichospitalbasedcrosssectionalstudyinturkey