Cargando…

C/EBP-Induced Transdifferentiation Reveals Granulocyte-Macrophage Precursor-like Plasticity of B Cells

The lymphoid-myeloid transdifferentiation potentials of members of the C/EBP family (C/EBPα, β, δ, and ε) were compared in v-Abl-immortalized primary B cells. Conversion of B cells to macrophages was readily induced by the ectopic expression of any C/EBP, and enhanced by endogenous C/EBPα and β acti...

Descripción completa

Detalles Bibliográficos
Autores principales: Cirovic, Branko, Schönheit, Jörg, Kowenz-Leutz, Elisabeth, Ivanovska, Jelena, Klement, Christine, Pronina, Nina, Bégay, Valérie, Leutz, Achim
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5312250/
https://www.ncbi.nlm.nih.gov/pubmed/28111277
http://dx.doi.org/10.1016/j.stemcr.2016.12.015