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C/EBP-Induced Transdifferentiation Reveals Granulocyte-Macrophage Precursor-like Plasticity of B Cells
The lymphoid-myeloid transdifferentiation potentials of members of the C/EBP family (C/EBPα, β, δ, and ε) were compared in v-Abl-immortalized primary B cells. Conversion of B cells to macrophages was readily induced by the ectopic expression of any C/EBP, and enhanced by endogenous C/EBPα and β acti...
Autores principales: | Cirovic, Branko, Schönheit, Jörg, Kowenz-Leutz, Elisabeth, Ivanovska, Jelena, Klement, Christine, Pronina, Nina, Bégay, Valérie, Leutz, Achim |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5312250/ https://www.ncbi.nlm.nih.gov/pubmed/28111277 http://dx.doi.org/10.1016/j.stemcr.2016.12.015 |
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