HuCNS-SC Human NSCs Fail to Differentiate, Form Ectopic Clusters, and Provide No Cognitive Benefits in a Transgenic Model of Alzheimer's Disease

Transplantation of neural stem cells (NSCs) can improve cognition in animal models of Alzheimer's disease (AD). However, AD is a protracted disorder, and prior studies have examined only short-term effects. We therefore used an immune-deficient model of AD (Rag-5xfAD mice) to examine long-term...

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Detalles Bibliográficos
Autores principales: Marsh, Samuel E., Yeung, Stephen T., Torres, Maria, Lau, Lydia, Davis, Joy L., Monuki, Edwin S., Poon, Wayne W., Blurton-Jones, Mathew
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5312253/
https://www.ncbi.nlm.nih.gov/pubmed/28199828
http://dx.doi.org/10.1016/j.stemcr.2016.12.019

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5312253/
https://www.ncbi.nlm.nih.gov/pubmed/28199828
http://dx.doi.org/10.1016/j.stemcr.2016.12.019

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