Common Telomere Changes during In Vivo Reprogramming and Early Stages of Tumorigenesis

Reprogramming of differentiated cells into induced pluripotent stem cells has been recently achieved in vivo in mice. Telomeres are essential for chromosomal stability and determine organismal life span as well as cancer growth. Here, we study whether tissue dedifferentiation induced by in vivo repr...

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Detalles Bibliográficos
Autores principales: Marión, Rosa M., López de Silanes, Isabel, Mosteiro, Lluc, Gamache, Benjamin, Abad, María, Guerra, Carmen, Megías, Diego, Serrano, Manuel, Blasco, Maria A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5312258/
https://www.ncbi.nlm.nih.gov/pubmed/28162998
http://dx.doi.org/10.1016/j.stemcr.2017.01.001

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5312258/
https://www.ncbi.nlm.nih.gov/pubmed/28162998
http://dx.doi.org/10.1016/j.stemcr.2017.01.001

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