PDCD4 is a CSL associated protein with a transcription repressive function in cancer associated fibroblast activation

The Notch/CSL pathway plays an important role in skin homeostasis and carcinogenesis. CSL, the key effector of canonical Notch signaling endowed with an intrinsic transcription repressive function, suppresses stromal fibroblast senescence and Cancer Associated Fibroblast (CAF) activation through dir...

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Detalles Bibliográficos
Autores principales: Jo, Seung-Hee, Kim, Dong Eun, Clocchiatti, Andrea, Dotto, G. Paolo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Priority Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5312270/
https://www.ncbi.nlm.nih.gov/pubmed/27542230
http://dx.doi.org/10.18632/oncotarget.11227

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5312270/
https://www.ncbi.nlm.nih.gov/pubmed/27542230
http://dx.doi.org/10.18632/oncotarget.11227

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