Efficacy of ATR inhibitors as single agents in Ewing sarcoma

Ewing sarcomas (ES) are pediatric bone tumors that arise from a driver translocation, most frequently EWS/FLI1. Current ES treatment involves DNA damaging agents, yet the basis for the sensitivity to these therapies remains unknown. Oncogene-induced replication stress (RS) is a known source of endog...

Descripción completa

Detalles Bibliográficos
Autores principales: Nieto-Soler, Maria, Morgado-Palacin, Isabel, Lafarga, Vanesa, Lecona, Emilio, Murga, Matilde, Callen, Elsa, Azorin, Daniel, Alonso, Javier, Lopez, Andres J., Nussenzweig, Andre, Fernandez-Capetillo, Oscar
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Priority Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5312273/
https://www.ncbi.nlm.nih.gov/pubmed/27577084
http://dx.doi.org/10.18632/oncotarget.11643

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5312273/
https://www.ncbi.nlm.nih.gov/pubmed/27577084
http://dx.doi.org/10.18632/oncotarget.11643

Ejemplares similares