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Efficacy of ATR inhibitors as single agents in Ewing sarcoma

Ewing sarcomas (ES) are pediatric bone tumors that arise from a driver translocation, most frequently EWS/FLI1. Current ES treatment involves DNA damaging agents, yet the basis for the sensitivity to these therapies remains unknown. Oncogene-induced replication stress (RS) is a known source of endog...

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Detalles Bibliográficos
Autores principales:	Nieto-Soler, Maria, Morgado-Palacin, Isabel, Lafarga, Vanesa, Lecona, Emilio, Murga, Matilde, Callen, Elsa, Azorin, Daniel, Alonso, Javier, Lopez, Andres J., Nussenzweig, Andre, Fernandez-Capetillo, Oscar
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Impact Journals LLC 2016
Materias:	Priority Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5312273/ https://www.ncbi.nlm.nih.gov/pubmed/27577084 http://dx.doi.org/10.18632/oncotarget.11643

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