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Zbtb1 prevents default myeloid differentiation of lymphoid-primed multipotent progenitors

Zbtb1 is a transcription factor that prevents DNA damage and p53-mediated apoptosis in replicating immune progenitors, affecting lymphoid as well as myeloid development when hematopoietic progenitors are in competition in mixed bone marrow chimeras. However, Zbtb1-deficient mice do not have an appar...

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Detalles Bibliográficos
Autores principales:	Zhang, Xianyu, Lu, Ying, Cao, Xin, Zhen, Tao, Kovalovsky, Damian
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Impact Journals LLC 2016
Materias:	Priority Research Paper: Immunology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5312274/ https://www.ncbi.nlm.nih.gov/pubmed/27542215 http://dx.doi.org/10.18632/oncotarget.11356

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