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Loss of NEDD4 contributes to RTP801 elevation and neuron toxicity: implications for Parkinson's disease
Parkinson's disease (PD) is a disorder characterized by the degeneration of certain neuronal populations in the central and peripheral nervous system. One of the hallmarks of the disease is the toxic accumulation of proteins within susceptible neurons due to major impairment in the degradation/...
Autores principales: | , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Impact Journals LLC
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5312278/ https://www.ncbi.nlm.nih.gov/pubmed/27494837 http://dx.doi.org/10.18632/oncotarget.11020 |