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Aloe-emodin inhibits HER-2 expression through the downregulation of Y-box binding protein-1 in HER-2-overexpressing human breast cancer cells

Human epidermal growth factor receptor-2 (HER-2)-positive breast cancer tends to be aggressive, highly metastatic, and drug resistant and spreads rapidly. Studies have indicated that emodin inhibits HER-2 expression. This study compared the HER-2-inhibitory effects of two compounds extracted from rh...

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Detalles Bibliográficos
Autores principales: Ma, Jui-Wen, Hung, Chao-Ming, Lin, Ying-Chao, Ho, Chi-Tang, Kao, Jung-Yie, Way, Tzong-Der
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5312285/
https://www.ncbi.nlm.nih.gov/pubmed/27391337
http://dx.doi.org/10.18632/oncotarget.10410