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The interplay between the lysine demethylase KDM1A and DNA methyltransferases in cancer cells is cell cycle dependent
DNA methylation and histone modifications are key epigenetic regulators of gene expression, and tight connections are known between the two. DNA methyltransferases are upregulated in several tumors and aberrant DNA methylation profiles are a cancer hallmark. On the other hand, histone demethylases a...
Autores principales: | , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Impact Journals LLC
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5312287/ https://www.ncbi.nlm.nih.gov/pubmed/27449289 http://dx.doi.org/10.18632/oncotarget.10624 |