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The interplay between the lysine demethylase KDM1A and DNA methyltransferases in cancer cells is cell cycle dependent

DNA methylation and histone modifications are key epigenetic regulators of gene expression, and tight connections are known between the two. DNA methyltransferases are upregulated in several tumors and aberrant DNA methylation profiles are a cancer hallmark. On the other hand, histone demethylases a...

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Detalles Bibliográficos
Autores principales: Brenner, Carmen, Luciani, Judith, Bizet, Martin, Ndlovu, Matladi, Josseaux, Eleonore, Dedeurwaerder, Sarah, Calonne, Emilie, Putmans, Pascale, Cartron, Pierre-Francois, Defrance, Matthieu, Fuks, François, Deplus, Rachel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5312287/
https://www.ncbi.nlm.nih.gov/pubmed/27449289
http://dx.doi.org/10.18632/oncotarget.10624

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