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The microRNA signature of patients with sunitinib failure: regulation of UHRF1 pathways by microRNA-101 in renal cell carcinoma

Molecular targeted therapy is a standard treatment for patients with advanced renal cell carcinoma (RCC). Sunitinib is one of the most common molecular-targeted drugs for metastatic RCC. Molecular mechanisms of sunitinib resistance in RCC cells is still ambiguous. The microRNA (miRNA) expression sig...

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Detalles Bibliográficos
Autores principales: Goto, Yusuke, Kurozumi, Akira, Nohata, Nijiro, Kojima, Satoko, Matsushita, Ryosuke, Yoshino, Hirofumi, Yamazaki, Kazuto, Ishida, Yasuo, Ichikawa, Tomohiko, Naya, Yukio, Seki, Naohiko
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5312296/
https://www.ncbi.nlm.nih.gov/pubmed/27487138
http://dx.doi.org/10.18632/oncotarget.10887