Vorinostat and hydroxychloroquine improve immunity and inhibit autophagy in metastatic colorectal cancer

Hydroxychloroquine (HCQ) enhances the anti-cancer activity of the histone deacetylase inhibitor, vorinostat (VOR), in pre-clinical models and early phase clinical studies of metastatic colorectal cancer (mCRC). Mechanisms could include autophagy inhibition, accumulation of ubiquitinated proteins, an...

Descripción completa

Detalles Bibliográficos
Autores principales: Patel, Sukeshi, Hurez, Vincent, Nawrocki, Steffan T., Goros, Martin, Michalek, Joel, Sarantopoulos, John, Curiel, Tyler, Mahalingam, Devalingam
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5312297/
https://www.ncbi.nlm.nih.gov/pubmed/27463016
http://dx.doi.org/10.18632/oncotarget.10824

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5312297/
https://www.ncbi.nlm.nih.gov/pubmed/27463016
http://dx.doi.org/10.18632/oncotarget.10824

Ejemplares similares