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Single-strand DNA library preparation improves sequencing of formalin-fixed and paraffin-embedded (FFPE) cancer DNA

DNA derived from formalin-fixed and paraffin-embedded (FFPE) tissue has been a challenge to large-scale genomic sequencing, due to its low quality and quantities. Improved techniques enabling the genome-wide analysis of FFPE material would be of great value, both from a research and clinical perspec...

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Detalles Bibliográficos
Autores principales: Stiller, Mathias, Sucker, Antje, Griewank, Klaus, Aust, Daniela, Baretton, Gustavo Bruno, Schadendorf, Dirk, Horn, Susanne
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5312299/
https://www.ncbi.nlm.nih.gov/pubmed/27463017
http://dx.doi.org/10.18632/oncotarget.10827