Apatinib inhibits cellular invasion and migration by fusion kinase KIF5B-RET via suppressing RET/Src signaling pathway

The Rearranged during transfection (RET) fusion gene is a newly identified oncogenic mutation in non-small cell lung cancer (NSCLC). The aim of this study is to explore the biological functions of the gene in tumorigenesis and metastasis in RET gene fusion-driven preclinical models. We also investig...

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Detalles Bibliográficos
Autores principales: Lin, Chen, Wang, Shanshan, Xie, Weiwei, Zheng, Rongliang, Gan, Yu, Chang, Jianhua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5312308/
https://www.ncbi.nlm.nih.gov/pubmed/27494860
http://dx.doi.org/10.18632/oncotarget.10985

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5312308/
https://www.ncbi.nlm.nih.gov/pubmed/27494860
http://dx.doi.org/10.18632/oncotarget.10985

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