FOXM1 confers resistance to gefitinib in lung adenocarcinoma via a MET/AKT-dependent positive feedback loop

Gefitinib resistance remains a major problem in the treatment of lung adenocarcinoma. However, the molecular mechanisms of gefitinib resistance are not fully understood. In this study, we characterized the critical role of transcription factor Forkhead box protein M1 (FOXM1) in gefitinib resistance...

Descripción completa

Detalles Bibliográficos
Autores principales: Wang, Yu, Zhang, Weiwei, Wen, Li, Yang, Huiling, Wen, Mingling, Yun, Yuyu, Zhao, Lisheng, Zhu, Xiaofei, Tian, Li, Luo, Erping, Li, Yu, Liu, Wenchao, Wen, Ning
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5312309/
https://www.ncbi.nlm.nih.gov/pubmed/27494877
http://dx.doi.org/10.18632/oncotarget.11043

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5312309/
https://www.ncbi.nlm.nih.gov/pubmed/27494877
http://dx.doi.org/10.18632/oncotarget.11043

Ejemplares similares