Cargando…

The human box C/D snoRNAs U3 and U8 are required for pre-rRNA processing and tumorigenesis

Small nucleolar RNAs (snoRNAs) are emerging as a novel class of proto-oncogenes and tumor suppressors; their involvement in tumorigenesis remains unclear. The box C/D snoRNAs U3 and U8 are upregulated in breast cancers. Here we characterize the function of human U3 and U8 in ribosome biogenesis, nuc...

Descripción completa

Detalles Bibliográficos
Autores principales: Langhendries, Jean-Louis, Nicolas, Emilien, Doumont, Gilles, Goldman, Serge, Lafontaine, Denis L.J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5312328/
https://www.ncbi.nlm.nih.gov/pubmed/27517747
http://dx.doi.org/10.18632/oncotarget.11148