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Oleandrin induces DNA damage responses in cancer cells by suppressing the expression of Rad51

Oleandrin is a monomeric compound extracted from leaves and seeds of Nerium oleander. It had been reported that oleandrin could effectively inhibit the growth of human cancer cells. However, the specific mechanisms of the oleandrin-induced anti-tumor effects remain largely unclear. Genomic instabili...

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Detalles Bibliográficos
Autores principales: Bao, Zhengqiang, Tian, Baoping, Wang, Xiaohui, Feng, Hanrong, Liang, Ye, Chen, Zhihua, Li, Wen, Shen, Huahao, Ying, Songmin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5312332/
https://www.ncbi.nlm.nih.gov/pubmed/27449097
http://dx.doi.org/10.18632/oncotarget.10726