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High expression of cholesterol biosynthesis genes is associated with resistance to statin treatment and inferior survival in breast cancer

There is sufficient evidence that statins have a protective role against breast cancer proliferation and recurrence, but treatment predictive biomarkers are lacking. Breast cancer cell lines displaying diverse sensitivity to atorvastatin were subjected to global transcriptional profiling and genes s...

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Detalles Bibliográficos
Autores principales: Kimbung, Siker, Lettiero, Barbara, Feldt, Maria, Bosch, Ana, Borgquist, Signe
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5312337/
https://www.ncbi.nlm.nih.gov/pubmed/27458152
http://dx.doi.org/10.18632/oncotarget.10746