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High expression of cholesterol biosynthesis genes is associated with resistance to statin treatment and inferior survival in breast cancer
There is sufficient evidence that statins have a protective role against breast cancer proliferation and recurrence, but treatment predictive biomarkers are lacking. Breast cancer cell lines displaying diverse sensitivity to atorvastatin were subjected to global transcriptional profiling and genes s...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Impact Journals LLC
2016
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5312337/ https://www.ncbi.nlm.nih.gov/pubmed/27458152 http://dx.doi.org/10.18632/oncotarget.10746 |