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miR-145 sensitizes breast cancer to doxorubicin by targeting multidrug resistance-associated protein-1

Multidrug resistance-associated protein 1 (MRP1) is an important efflux transporter and overexpression of MRP1 usually leads to chemoresistance in breast cancer. Here, we found MRP1 overexpressed in human breast cancer tissues and breast cancer cell lines (compared with normal breast tissues and cel...

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Detalles Bibliográficos
Autores principales: Gao, Man, Miao, Lingling, Liu, Mingxia, Li, Chenggang, Yu, Cunzhi, Yan, Hong, Yin, Yongxiang, Wang, Yizheng, Qi, Xinming, Ren, Jin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5312343/
https://www.ncbi.nlm.nih.gov/pubmed/27487127
http://dx.doi.org/10.18632/oncotarget.10845