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MicroRNA 10b promotes abnormal expression of the proto-oncogene c-Jun in metastatic breast cancer cells

MicroRNAs have been shown to act as oncogenes or tumor suppressers via various cellular pathways. Specifically, in breast cancer, upregulation of miR-10b is positively associated with aggressiveness of tumors. However, the mechanism by which miR-10b contributes to cell malignancy is largely unknown....

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Detalles Bibliográficos
Autores principales: Knirsh, Revital, Ben-Dror, Iris, Modai, Shira, Shomron, Noam, Vardimon, Lily
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5312359/
https://www.ncbi.nlm.nih.gov/pubmed/27494896
http://dx.doi.org/10.18632/oncotarget.11000