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A lupus anti-DNA autoantibody mediates autocatalytic, targeted delivery of nanoparticles to tumors

Strategies to target nanoparticles to tumors that rely on surface modification with ligands that bind molecules overexpressed on cancer cells or the tumor neovasculature suffer from a major limitation: with delivery of toxic agents the amount of molecules available for targeting decreases with time;...

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Detalles Bibliográficos
Autores principales: Chen, Zeming, Patel, Jaymin M., Noble, Philip W., Garcia, Cesar, Hong, Zhangyong, Hansen, James E., Zhou, Jiangbing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5312362/
https://www.ncbi.nlm.nih.gov/pubmed/27494868
http://dx.doi.org/10.18632/oncotarget.11015