The Fanconi anemia pathway controls oncogenic response in hematopoietic stem and progenitor cells by regulating PRMT5-mediated p53 arginine methylation

The Fanconi anemia (FA) pathway is involved in DNA damage and other cellular stress responses. We have investigated the role of the FA pathway in oncogenic stress response by employing an in vivo stress-response model expressing the Gadd45β-luciferase transgene. Using two inducible models of oncogen...

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Detalles Bibliográficos
Autores principales: Du, Wei, Amarachintha, Surya, Erden, Ozlem, Wilson, Andrew, Pang, Qishen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5312365/
https://www.ncbi.nlm.nih.gov/pubmed/27507053
http://dx.doi.org/10.18632/oncotarget.11088

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5312365/
https://www.ncbi.nlm.nih.gov/pubmed/27507053
http://dx.doi.org/10.18632/oncotarget.11088

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