SC79 protects retinal pigment epithelium cells from UV radiation via activating Akt-Nrf2 signaling

Excessive Ultra-violet (UV) radiation causes oxidative damages and apoptosis in retinal pigment epithelium (RPE) cells. Here we tested the potential activity of SC79, a novel small molecule activator of Akt, against the process. We showed that SC79 activated Akt in primary and established (ARPE-19 l...

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Detalles Bibliográficos
Autores principales: Gong, Yi-qing, Huang, Wei, Li, Ke-ran, Liu, Yuan-yuan, Cao, Guo-fan, Cao, Cong, Jiang, Qin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5312373/
https://www.ncbi.nlm.nih.gov/pubmed/27517753
http://dx.doi.org/10.18632/oncotarget.11164

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5312373/
https://www.ncbi.nlm.nih.gov/pubmed/27517753
http://dx.doi.org/10.18632/oncotarget.11164

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