Superior efficacy of co-treatment with the dual PI3K/mTOR inhibitor BEZ235 and histone deacetylase inhibitor Trichostatin A against NSCLC

Non-small-cell lung cancer (NSCLC) is the leading cause of cancer-related death worldwide. NSCLC development and progression have recently been correlated with the heightened activation of histone deacetylases (HDACs) and PI3K/Akt signaling pathways. Targeted inhibition of these proteins is promisin...

Descripción completa

Detalles Bibliográficos
Autores principales: Piao, Junjie, Chen, Liyan, Quan, Taihao, Li, Longshan, Quan, Chunji, Piao, Yingshi, Jin, Tiefeng, Lin, Zhenhua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5312376/
https://www.ncbi.nlm.nih.gov/pubmed/27507059
http://dx.doi.org/10.18632/oncotarget.11109

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5312376/
https://www.ncbi.nlm.nih.gov/pubmed/27507059
http://dx.doi.org/10.18632/oncotarget.11109

Ejemplares similares