Suppression of c-Myc and RRM2 expression in pancreatic cancer cells by the sphingosine kinase-2 inhibitor ABC294640

Pancreatic cancer remains extremely difficult to treat, with the average lifespan following diagnosis being only 3-6 months, resulting in a death to incidence ratio of 0.94. A major reason for this high mortality rate is resistance to the main chemotherapeutic agent used to treat this disease, gemci...

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Detalles Bibliográficos
Autores principales: Lewis, Clayton S., Voelkel-Johnson, Christina, Smith, Charles D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5312377/
https://www.ncbi.nlm.nih.gov/pubmed/27517489
http://dx.doi.org/10.18632/oncotarget.11112

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5312377/
https://www.ncbi.nlm.nih.gov/pubmed/27517489
http://dx.doi.org/10.18632/oncotarget.11112

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