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Wnt signalling is a bi-directional vulnerability of cancer cells

Wnt signalling is involved in the formation, metastasis and relapse of a wide array of cancers. However, there is ongoing debate as to whether activation or inhibition of the pathway holds the most promise as a therapeutic treatment for cancer, with conflicting evidence from a variety of tumour type...

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Detalles Bibliográficos
Autores principales: Duffy, David J., Krstic, Aleksandar, Schwarzl, Thomas, Halasz, Melinda, Iljin, Kristiina, Fey, Dirk, Haley, Bridget, Whilde, Jenny, Haapa-Paananen, Saija, Fey, Vidal, Fischer, Matthias, Westermann, Frank, Henrich, Kai-Oliver, Bannert, Steffen, Higgins, Desmond G., Kolch, Walter
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5312386/
https://www.ncbi.nlm.nih.gov/pubmed/27531891
http://dx.doi.org/10.18632/oncotarget.11203