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Ephrin B3 interacts with multiple EphA receptors and drives migration and invasion in non-small cell lung cancer

Ephrin receptors (Ephs) are reported to control metastatic signaling of non-small cell lung cancer (NSCLC) and other tumors. Here we show for the first time that blocking expression of the Eph ligand Ephrin B3 inhibits NSCLC cell migration and invasion. We demonstrate that Ephrin B3 directly binds t...

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Detalles Bibliográficos
Autores principales: Efazat, Ghazal, Novak, Metka, Kaminskyy, Vitaliy O., Petris, Luigi De, Kanter, Lena, Juntti, Therese, Bergman, Per, Zhivotovsky, Boris, Lewensohn, Rolf, Hååg, Petra, Viktorsson, Kristina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5312387/
https://www.ncbi.nlm.nih.gov/pubmed/27533087
http://dx.doi.org/10.18632/oncotarget.11219