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Lin28A activates androgen receptor via regulation of c-myc and promotes malignancy of ER−/Her2+ breast cancer

Having previously demonstrated the co-expression status of the Lin28A and androgen receptor (AR) in ER−/Her2+ breast cancer, we tested the hypothesis that Lin28A can activate AR and promotes growth of ER−/Her2+ breast cancer. The expression of Lin28A and AR were examined after Lin28A siRNA and Lin28...

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Detalles Bibliográficos
Autores principales: Shen, Honghong, Zhao, Lin, Feng, Xiaolong, Xu, Cong, Li, Congying, Niu, Yun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5312392/
https://www.ncbi.nlm.nih.gov/pubmed/27494865
http://dx.doi.org/10.18632/oncotarget.11004