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A single nucleotide polymorphism genotyping platform for the authentication of patient derived xenografts

Patient derived xenografts (PDXs) have become a vital, frequently used, component of anti-cancer drug development. PDXs can be serially passaged in vivo for years, and shared across laboratories. As a consequence, the potential for mis-identification and cross-contamination is possible, yet authenti...

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Detalles Bibliográficos
Autores principales: El-Hoss, Jad, Jing, Duohui, Evans, Kathryn, Toscan, Cara, Xie, Jinhan, Lee, Hyunjoo, Taylor, Renea A., Lawrence, Mitchell G., Risbridger, Gail P., MacKenzie, Karen L., Sutton, Rosemary, Lock, Richard B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5312397/
https://www.ncbi.nlm.nih.gov/pubmed/27528024
http://dx.doi.org/10.18632/oncotarget.11125