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Role of Nrf2 and protective effects of Metformin against tobacco smoke-induced cerebrovascular toxicity

Cigarette smoking (CS) is associated with vascular endothelial dysfunction in a causative way primarily related to the TS content of reactive oxygen species (ROS), nicotine, and inflammation. TS promotes glucose intolerance and increases the risk of developing type-2 diabetes mellitus (2DM) with whi...

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Detalles Bibliográficos
Autores principales: Prasad, Shikha, Sajja, Ravi K., Kaisar, Mohammad Abul, Park, Jee Hyun, Villalba, Heidi, Liles, Taylor, Abbruscato, Thomas, Cucullo, Luca
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5312505/
https://www.ncbi.nlm.nih.gov/pubmed/28212524
http://dx.doi.org/10.1016/j.redox.2017.02.007