Cargando…

Role of Nrf2 and protective effects of Metformin against tobacco smoke-induced cerebrovascular toxicity

Cigarette smoking (CS) is associated with vascular endothelial dysfunction in a causative way primarily related to the TS content of reactive oxygen species (ROS), nicotine, and inflammation. TS promotes glucose intolerance and increases the risk of developing type-2 diabetes mellitus (2DM) with whi...

Descripción completa

Detalles Bibliográficos
Autores principales:	Prasad, Shikha, Sajja, Ravi K., Kaisar, Mohammad Abul, Park, Jee Hyun, Villalba, Heidi, Liles, Taylor, Abbruscato, Thomas, Cucullo, Luca
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier 2017
Materias:	Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5312505/ https://www.ncbi.nlm.nih.gov/pubmed/28212524 http://dx.doi.org/10.1016/j.redox.2017.02.007

Ejemplares similares

Offsetting the impact of smoking and e-cigarette vaping on the cerebrovascular system and stroke injury: Is Metformin a viable countermeasure?
por: Kaisar, Mohammad A., et al.
Publicado: (2017)

Impact of cigarette smoke extract and hyperglycemic conditions on blood–brain barrier endothelial cells
por: Prasad, Shikha, et al.
Publicado: (2015)

Differential Cerebrovascular Toxicity of Various Tobacco Products: A Regulatory Perspective
por: Sajja, Ravi K, et al.
Publicado: (2015)

Impact of Tobacco Smoking and Type-2 Diabetes Mellitus on Public Health: A Cerebrovascular Perspective
por: Prasad, Shikha, et al.
Publicado: (2015)

Anti-Diabetic Countermeasures Against Tobacco Smoke-Dependent Cerebrovascular Toxicity: Use and Effect of Rosiglitazone
por: Sivandzade, Farzane, et al.
Publicado: (2019)

Unhealthy smokers: scopes for prophylactic intervention and clinical treatment
por: Prasad, Shikha, et al.
Publicado: (2017)

NRF2 and NF-қB interplay in cerebrovascular and neurodegenerative disorders: Molecular mechanisms and possible therapeutic approaches
por: Sivandzade, Farzane, et al.
Publicado: (2018)

In Vitro Modulation of Redox and Metabolism Interplay at the Brain Vascular Endothelium: Genomic and Proteomic Profiles of Sulforaphane Activity
por: Sajja, Ravi K., et al.
Publicado: (2018)

Impact of altered glycaemia on blood-brain barrier endothelium: an in vitro study using the hCMEC/D3 cell line
por: Sajja, Ravi K, et al.
Publicado: (2014)

A convenient UHPLC-MS/MS method for routine monitoring of plasma and brain levels of nicotine and cotinine as a tool to validate newly developed preclinical smoking model in mouse
por: Kaisar, Mohammad A., et al.
Publicado: (2017)

Effect of full flavor and denicotinized cigarettes exposure on the brain microvascular endothelium: a microarray-based gene expression study using a human immortalized BBB endothelial cell line
por: Naik, Pooja, et al.
Publicado: (2015)

Cerebrovascular and Neurological Disorders: Protective Role of NRF2
por: Sivandzade, Farzane, et al.
Publicado: (2019)

Altered Nrf2 Signaling Mediates Hypoglycemia-Induced Blood–Brain Barrier Endothelial Dysfunction In Vitro
por: Sajja, Ravi K., et al.
Publicado: (2015)

Comparative assessment of in vitro BBB tight junction integrity following exposure to cigarette smoke and e-cigarette vapor: a quantitative evaluation of the protective effects of metformin using small-molecular-weight paracellular markers
por: Kadry, Hossam, et al.
Publicado: (2021)

Oxidative and pro-inflammatory impact of regular and denicotinized cigarettes on blood brain barrier endothelial cells: is smoking reduced or nicotine-free products really safe?
por: Naik, Pooja, et al.
Publicado: (2014)

Harmful Effects of Smoking Cannabis: A Cerebrovascular and Neurological Perspective
por: Archie, Sabrina Rahman, et al.
Publicado: (2019)

Pathophysiological Impact of Cigarette Smoke Exposure on the Cerebrovascular System with a Focus on the Blood-brain Barrier: Expanding the Awareness of Smoking Toxicity in an Underappreciated Area
por: Mazzone, Peter, et al.
Publicado: (2010)

In Vitro Assessment of Tobacco Smoke Toxicity at the BBB: Do Antioxidant Supplements Have a Protective Role?
por: Hossain, Mohammed, et al.
Publicado: (2011)

Cerebrovascular and Neurological Dysfunction under the Threat of COVID-19: Is There a Comorbid Role for Smoking and Vaping?
por: Archie, Sabrina Rahman, et al.
Publicado: (2020)

Pathobiology of tobacco smoking and neurovascular disorders: untied strings and alternative products
por: Naik, Pooja, et al.
Publicado: (2015)

The cerebrovascular and neurological impact of chronic smoking on post-traumatic brain injury outcome and recovery: an in vivo study
por: Sivandzade, Farzane, et al.
Publicado: (2020)

In vitro characterization of odorranalectin for peptide-based drug delivery across the blood–brain barrier
por: Sajja, Ravi K., et al.
Publicado: (2019)

HIV-1 gp120 and tobacco smoke synergistically disrupt the integrity of the blood-brain barrier
por: Bhalerao, Aditya, et al.
Publicado: (2022)

Proximate Mediators of Microvascular Dysfunction at the Blood-Brain Barrier: Neuroinflammatory Pathways to Neurodegeneration
por: Festoff, Barry W., et al.
Publicado: (2017)

Assessing the protective effect of rosiglitazone against electronic cigarette/tobacco smoke-induced blood–brain barrier impairment
por: Sivandzade, Farzane, et al.
Publicado: (2019)

Membrane Transporters and Pharmacological Implications
por: Cucullo, Luca, et al.
Publicado: (2016)

Permeability of Metformin across an In Vitro Blood–Brain Barrier Model during Normoxia and Oxygen-Glucose Deprivation Conditions: Role of Organic Cation Transporters (Octs)
por: Sharma, Sejal, et al.
Publicado: (2023)

OTC Antioxidant Products for the Treatment of Cardiovascular and other Disorders: Popular Myth or Fact?
por: Kaisar, Mohammad A., et al.
Publicado: (2015)

HMGB1 and thrombin mediate the blood-brain barrier dysfunction acting as biomarkers of neuroinflammation and progression to neurodegeneration in Alzheimer’s disease
por: Festoff, Barry W., et al.
Publicado: (2016)

Short-term exposure to JUUL electronic cigarettes can worsen ischemic stroke outcome
por: Sifat, Ali Ehsan, et al.
Publicado: (2022)

Pulmonary toxicity of chronic exposure to tobacco and biomass smoke in rats
por: Dogan, Omer Tamer, et al.
Publicado: (2011)

A new dynamic in vitro modular capillaries-venules modular system: Cerebrovascular physiology in a box
por: Cucullo, Luca, et al.
Publicado: (2013)

Metformin toxicity: A meta-summary of case reports
por: Juneja, Deven, et al.
Publicado: (2022)

Toxicant content, physical properties and biological activity of waterpipe tobacco smoke and its tobacco-free alternatives
por: Shihadeh, Alan, et al.
Publicado: (2015)

Tobacco Smoke
Publicado: (1894)

Smoking Tobacco
Publicado: (1861)

Tobacco Smoke
Publicado: (1885)

Smoking Tobacco
Publicado: (1880)

Biological activity of tobacco smoke and tobacco smoke-related chemicals.
por: Kouri, R E, et al.
Publicado: (1979)

Characterization of Toxic Metals in Tobacco, Tobacco Smoke, and Cigarette Ash from Selected Imported and Local Brands in Pakistan
por: Ajab, Huma, et al.
Publicado: (2014)

Cannot write session to /tmp/vufind_sessions/sess_u6fog9n27ijj6v9s9ijct53mhe