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The microtubule plus-end-tracking protein TACC3 promotes persistent axon outgrowth and mediates responses to axon guidance signals during development

BACKGROUND: Formation of precise neuronal connections requires proper axon guidance. Microtubules (MTs) of the growth cone provide a critical driving force during navigation of the growing ends of axons. Pioneer MTs and their plus-end tracking proteins (+TIPs) are thought to play integrative roles d...

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Detalles Bibliográficos
Autores principales: Erdogan, Burcu, Cammarata, Garrett M., Lee, Eric J., Pratt, Benjamin C., Francl, Andrew F., Rutherford, Erin L., Lowery, Laura Anne
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5312526/
https://www.ncbi.nlm.nih.gov/pubmed/28202041
http://dx.doi.org/10.1186/s13064-017-0080-7